ABC Wednesday 9:00 PM (30 min.) Premiered: September 24, 1958 Last Aired: March 19, 1966 Show Category: Comedy The Donna Reed Show premiered on September 24, 1958, on ABC. The show revolves around housewife, Donna Stone, and her family--husband Alex who is a pediatrician, 14 year-old Mary, and 11 year-old Jeff. The Stone family reside in the midwestern town of Hilldale. Donna was the perfect American housewife and mother. She was always neatly-groomed, lovely, good-natured, thoughtful, and ...